1. Olig2 is normally expressed in the ventral area of the neural tube . 2. Amniotic fluid acetylcholinesterase and specific than AFP in predicting neural tube defects. 3. Immunohistochemically, neural tube -like structures are vimentin positive in the majority of medulloepitheliomas. 4. Later in development, neurulation causes the neurectoderm to form the neural tube . 5. Ferroportin-1 plays an important role in neural tube closure and forebrain patterning. 6. The formation of the neural tube from the ectoderm is called neurulation. 7. BMP7 is crucial for kidney development, sperm synthesis, and neural tube polarization. 8. There are five distinct progenitor domains in the ventral neural tube , viz. 9. Early in pregnancy, the neural tube creates the brain, skull and spine. 10. The spinal cord is made from part of the neural tube during development. 
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